Silver-catalyzed nitrogenation of alkynes: a direct approach to nitriles through C≡C bond cleavage.
نویسندگان
چکیده
منابع مشابه
Copper-catalyzed direct transformation of simple alkynes to alkenyl nitriles via aerobic oxidative N-incorporation
A novel direct transformation of aliphatic terminal alkynes to alkenyl nitriles through the incorporation of a nitrogen atom into the simple hydrocarbons has been reported. The usage of inexpensive copper catalyst, O2 as the sole oxidant, broad substrate scope as well as feasibility for “late-stage modification” make this protocol very promising. Mechanistic studies including DFT calculation de...
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Cycloadditions of azides with alkynes to form triazoles under thermal conditions (Huisgen cycloaddition) or in the presence of copper [click reaction, copper-catalyzed azide– alkyne cycloaddition (CuAAC)] are reactions of fundamental importance in organic chemistry. Triazoles can also be obtained by means of ruthenium, silver, and iridium catalysis, as well as by a zinc-mediated process. In sha...
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The direct addition of ortho C-H bonds in various aromatic compounds such as ketones, esters, imines, imidates, nitriles, and aldehydes to olefins and acetylenes can be achieved with the aid of transition metal catalysts. The ruthenium catalyzed reaction is usually highly efficient and useful as a general synthetic method. The coordination to the metal center by a heteroatom in a directing grou...
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عنوان ژورنال:
- Angewandte Chemie
دوره 52 26 شماره
صفحات -
تاریخ انتشار 2013